Import a model

Select a file and upload it
Options
Input file (see the supported formats below)
Interpret metabolite identifiersYes No
Utilize metabolite cross-referencesbiggM
chebi
chem
envipathM
hmdb
keggC
keggD
keggE
keggG
lipidmapsM
metacycM
reactomeM
rheaG
rheaP
sabiorkM
seedM
slm

Instructions
WhatComment
PrincipleThe Import method attempts to upload a user-supplied GEM and map it on the MNXref namespace. An importation report is created that documents the encountered difficulties during the mapping.
Various input formats are supported, including all those produced by MetaNetX. Various flavours of the SMBL format are supported, including some idiosyncratic usages of the SBML notes. The use of SBML compliant with the 3.1 specifications is however strongly recommended.
FormatThe syntax for text files is given in the model internals documentation.
Regarding the SBML file, it is strongly recommended to supply cross references using Identifiers.org-compliant annotations.
MappingThe following identifiers are recognized and mapped to the MNXref namespace
  • the special identifiers: BIOMASS and BOUNDARY
  • the identifiers describing chemical compounds, i.e. metabolites with the prefix MNXM (e.g. MNXM10)
  • the identifiers describing cellular compartments with the prefix MNXC (e.g. MNXC3); and with the prefix MNXD for the generic compartments
  • the identifiers of the form database:entry are mapped to the MNXref namespace IF possible, e.g. CHEBI:15422. Note that this feature is not supported for SBML model
However
  • chemical compounds or cellular compartments not participating in any reaction are automatically removed
General adviceSince, metabolic networks are complex objects combining biochemical, genetic, and genomic information, we recommend new MetaNetX users to practice the following steps
  • Pick a model from the repository (e.g. bigg_iAF1260)
  • Export it as an SBML file, or as a compressed text file (recommended for this exercise)
  • Introduce a small modification in the downloaded model, for example, modify the flux constraints on a single boundary (external) reaction
  • Upload the modified model under a new name
  • Use MetaNetX.org to compare the original model with the modified one
DisclaimerMetaNetX is not responsible for malformed file or syntax errors and will not offer user support on these issues.
We are unfortunately aware that some public genome-scale metabolic networks distributed in SBML format are not 100% compliant with the SBML specifications; or with our editorial choices. As a consequence, their import might be problematic. We recommend checking if a version of such model already exists in the MetaNetX repository.