Search MNXref
 Feedback

corticotropin-releasing hormone (human)

PropertiesImage
MNX_IDMNXM104054 Image of MNXM104054
referencechebi:65312
formulaC209H346N60O62S2
global charge0
mol weight4755.559
InChIKeyKLVRDXBAMSPYKH-RKYZNNDCSA-N
InChIInChI=1S/C209H346N60O62S2/c1-31-108(22)163(166(216)291)265-204(329)165(110(24)33-3)266-185(310)130(59-68-158(285)286)244-183(308)132(71-79-333-30)247-188(313)135(81-100(6)7)251-177(302)119(46-37-38-72-210)238-175(300)121(48-40-74-226-208(219)220)240-195(320)144(90-153(215)276)257-198(323)146(95-271)261-194(319)142(88-116-92-223-97-228-116)249-170(295)114(28)231-173(298)123(52-61-150(212)273)241-178(303)124(53-62-151(213)274)235-169(294)113(27)233-186(311)134(80-99(4)5)250-182(307)125(54-63-152(214)275)242-179(304)126(55-64-154(277)278)236-168(293)112(26)230-172(297)120(47-39-73-225-207(217)218)234-167(292)111(25)232-174(299)131(70-78-332-29)246-180(305)128(57-66-156(281)282)245-189(314)139(85-104(14)15)259-201(326)161(106(18)19)263-184(309)129(58-67-157(283)284)243-176(301)122(49-41-75-227-209(221)222)239-187(312)136(82-101(8)9)252-190(315)137(83-102(10)11)253-193(318)143(89-117-93-224-98-229-117)256-192(317)141(87-115-44-35-34-36-45-115)260-202(327)162(107(20)21)264-197(322)140(86-105(16)17)254-196(321)145(91-160(289)290)258-191(316)138(84-103(12)13)255-199(324)147(96-272)262-203(328)164(109(23)32-2)267-200(325)148-50-42-76-268(148)206(331)149-51-43-77-269(149)205(330)133(60-69-159(287)288)248-181(306)127(56-65-155(279)280)237-171(296)118(211)94-270/h34-36,44-45,92-93,97-114,118-149,161-165,270-272H,31-33,37-43,46-91,94-96,210-211H2,1-30H3,(H2,212,273)(H2,213,274)(H2,214,275)(H2,215,276)(H2,216,291)(H,223,228)(H,224,229)(H,230,297)(H,231,298)(H,232,299)(H,233,311)(H,234,292)(H,235,294)(H,236,293)(H,237,296)(H,238,300)(H,239,312)(H,240,320)(H,241,303)(H,242,304)(H,243,301)(H,244,308)(H,245,314)(H,246,305)(H,247,313)(H,248,306)(H,249,295)(H,250,307)(H,251,302)(H,252,315)(H,253,318)(H,254,321)(H,255,324)(H,256,317)(H,257,323)(H,258,316)(H,259,326)(H,260,327)(H,261,319)(H,262,328)(H,263,309)(H,264,322)(H,265,329)(H,266,310)(H,267,325)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H4,217,218,225)(H4,219,220,226)(H4,221,222,227)/t108-,109-,110-,111-,112-,113-,114-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,161-,162-,163-,164-,165-/m0/s1
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CO)[C@@H](C)CC)C(C)C)C(C)C)[C@@H](C)CC)C(N)=O
MNX internals
InChI (mnx)InChI=1/C209H346N60O62S2/c1-31-108(22)163(166(216)291)265-204(329)165(110(24)33-3)266-185(310)130(59-68-158(285)286)244-183(308)132(71-79-333-30)247-188(313)135(81-100(6)7)251-177(302)119(46-37-38-72-210)238-175(300)121(48-40-74-226-208(219)220)240-195(320)144(90-153(215)276)257-198(323)146(95-271)261-194(319)142(88-116-92-223-97-228-116)249-170(295)114(28)231-173(298)123(52-61-150(212)273)241-178(303)124(53-62-151(213)274)235-169(294)113(27)233-186(311)134(80-99(4)5)250-182(307)125(54-63-152(214)275)242-179(304)126(55-64-154(277)278)236-168(293)112(26)230-172(297)120(47-39-73-225-207(217)218)234-167(292)111(25)232-174(299)131(70-78-332-29)246-180(305)128(57-66-156(281)282)245-189(314)139(85-104(14)15)259-201(326)161(106(18)19)263-184(309)129(58-67-157(283)284)243-176(301)122(49-41-75-227-209(221)222)239-187(312)136(82-101(8)9)252-190(315)137(83-102(10)11)253-193(318)143(89-117-93-224-98-229-117)256-192(317)141(87-115-44-35-34-36-45-115)260-202(327)162(107(20)21)264-197(322)140(86-105(16)17)254-196(321)145(91-160(289)290)258-191(316)138(84-103(12)13)255-199(324)147(96-272)262-203(328)164(109(23)32-2)267-200(325)148-50-42-76-268(148)206(331)149-51-43-77-269(149)205(330)133(60-69-159(287)288)248-181(306)127(56-65-155(279)280)237-171(296)118(211)94-270/h34-36,44-45,92-93,97-114,118-149,161-165,270-272H,31-33,37-43,46-91,94-96,210-211H2,1-30H3,(H2,212,273)(H2,213,274)(H2,214,275)(H2,215,276)(H2,216,291)(H,223,228)(H,224,229)(H,230,297)(H,231,298)(H,232,299)(H,233,311)(H,234,292)(H,235,294)(H,236,293)(H,237,296)(H,238,300)(H,239,312)(H,240,320)(H,241,303)(H,242,304)(H,243,301)(H,244,308)(H,245,314)(H,246,305)(H,247,313)(H,248,306)(H,249,295)(H,250,307)(H,251,302)(H,252,315)(H,253,318)(H,254,321)(H,255,324)(H,256,317)(H,257,323)(H,258,316)(H,259,326)(H,260,327)(H,261,319)(H,262,328)(H,263,309)(H,264,322)(H,265,329)(H,266,310)(H,267,325)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H4,217,218,225)(H4,219,220,226)(H4,221,222,227)/t108-,109-,110-,111-,112-,113-,114-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,161-,162-,163-,164-,165-/m0/s1 Image of MNXM104054
SMILES (mnx)[CH3:1][CH2:31][C@H:108]([CH3:22])[C@@H:163]([C:166](=[NH:216])[OH:291])[N:265]=[C:204]([C@H:165]([C@@H:110]([CH3:24])[CH2:33][CH3:3])[N:266]=[C:185]([C@H:130]([CH2:59][CH2:68][C:158](=[O:285])[OH:286])[N:244]=[C:183]([C@H:132]([CH2:71][CH2:79][S:333][CH3:30])[N:247]=[C:188]([C@H:135]([CH2:81][CH:100]([CH3:6])[CH3:7])[N:251]=[C:177]([C@H:119]([CH2:46][CH2:37][CH2:38][CH2:72][NH2:210])[N:238]=[C:175]([C@H:121]([CH2:48][CH2:40][CH2:74][NH:226][C:208](=[NH:219])[NH2:220])[N:240]=[C:195]([C@H:144]([CH2:90][C:153](=[NH:215])[OH:276])[N:257]=[C:198]([C@H:146]([CH2:95][OH:271])[N:261]=[C:194]([C@H:142]([CH2:88][C:116]1=[CH:92][N:223]=[CH:97][NH:228]1)[N:249]=[C:170]([C@H:114]([CH3:28])[N:231]=[C:173]([C@H:123]([CH2:52][CH2:61][C:150](=[NH:212])[OH:273])[N:241]=[C:178]([C@H:124]([CH2:53][CH2:62][C:151](=[NH:213])[OH:274])[N:235]=[C:169]([C@H:113]([CH3:27])[N:233]=[C:186]([C@H:134]([CH2:80][CH:99]([CH3:4])[CH3:5])[N:250]=[C:182]([C@H:125]([CH2:54][CH2:63][C:152](=[NH:214])[OH:275])[N:242]=[C:179]([C@H:126]([CH2:55][CH2:64][C:154](=[O:277])[OH:278])[N:236]=[C:168]([C@H:112]([CH3:26])[N:230]=[C:172]([C@H:120]([CH2:47][CH2:39][CH2:73][NH:225][C:207](=[NH:217])[NH2:218])[N:234]=[C:167]([C@H:111]([CH3:25])[N:232]=[C:174]([C@H:131]([CH2:70][CH2:78][S:332][CH3:29])[N:246]=[C:180]([C@H:128]([CH2:57][CH2:66][C:156](=[O:281])[OH:282])[N:245]=[C:189]([C@H:139]([CH2:85][CH:104]([CH3:14])[CH3:15])[N:259]=[C:201]([C@H:161]([CH:106]([CH3:18])[CH3:19])[N:263]=[C:184]([C@H:129]([CH2:58][CH2:67][C:157](=[O:283])[OH:284])[N:243]=[C:176]([C@H:122]([CH2:49][CH2:41][CH2:75][NH:227][C:209](=[NH:221])[NH2:222])[N:239]=[C:187]([C@H:136]([CH2:82][CH:101]([CH3:8])[CH3:9])[N:252]=[C:190]([C@H:137]([CH2:83][CH:102]([CH3:10])[CH3:11])[N:253]=[C:193]([C@H:143]([CH2:89][C:117]1=[CH:93][N:224]=[CH:98][NH:229]1)[N:256]=[C:192]([C@H:141]([CH2:87][C:115]1=[CH:44][CH:35]=[CH:34][CH:36]=[CH:45]1)[N:260]=[C:202]([C@H:162]([CH:107]([CH3:20])[CH3:21])[N:264]=[C:197]([C@H:140]([CH2:86][CH:105]([CH3:16])[CH3:17])[N:254]=[C:196]([C@H:145]([CH2:91][C:160](=[O:289])[OH:290])[N:258]=[C:191]([C@H:138]([CH2:84][CH:103]([CH3:12])[CH3:13])[N:255]=[C:199]([C@H:147]([CH2:96][OH:272])[N:262]=[C:203]([C@H:164]([C@@H:109]([CH3:23])[CH2:32][CH3:2])[N:267]=[C:200]([C@@H:148]1[CH2:50][CH2:42][CH2:76][N:268]1[C:206]([C@@H:149]1[CH2:51][CH2:43][CH2:77][N:269]1[C:205]([C@H:133]([CH2:60][CH2:69][C:159](=[O:287])[OH:288])[N:248]=[C:181]([C@H:127]([CH2:56][CH2:65][C:155](=[O:279])[OH:280])[N:237]=[C:171]([C@H:118]([CH2:94][OH:270])[NH2:211])[OH:296])[OH:306])=[O:330])=[O:331])[OH:325])[OH:328])[OH:324])[OH:316])[OH:321])[OH:322])[OH:327])[OH:317])[OH:318])[OH:315])[OH:312])[OH:301])[OH:309])[OH:326])[OH:314])[OH:305])[OH:299])[OH:292])[OH:297])[OH:293])[OH:304])[OH:307])[OH:311])[OH:294])[OH:303])[OH:298])[OH:295])[OH:319])[OH:323])[OH:320])[OH:300])[OH:302])[OH:313])[OH:308])[OH:310])[OH:329]
Parent-child relations graph
Occurences in reactions#reac
in my sandbox 0
in MNXref (generic)0
in models (compartimentalized) 0
Similar chemical compounds in external resources
IdentifierDescription

CHEBI:65312
chebi:65312
KLVRDXBAMSPYKH-RKYZNNDCSA-N 		corticotropin-releasing hormone (human)
CRH
Corticoliberin
Corticotropin releasing hormone
L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-isoleucyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-valyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-alpha-glutamyl-L-valyl-L-leucyl-L-alpha-glutamyl-L-methionyl-L-alanyl-L-arginyl-L-alanyl-L-alpha-glutamyl-L-glutaminyl-L-leucyl-L-alanyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-histidyl-L-seryl-L-asparaginyl-L-arginyl-L-lysyl-L-leucyl-L-methionyl-L-alpha-glutamyl-L-isoleucyl-L-isoleucinamide
SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII-NH2
Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2
corticotropin-releasing factor (human)
corticotropin-releasing factor (human/rat)
human/rat CRF
hmdb:HMDB0250461
KLVRDXBAMSPYKH-UHFFFAOYSA-N 		Corticoliberin