MetaNetX
Automated Model Construction and Genome Annotation for Large-Scale Metabolic Networks

Feedback

(6S)-5-formyl-5,6,7,8-tetrahydrofolate

	Properties	Image
MNX_ID	MNXM1091982
reference	chebi:57457
formula	C₂₀H₂₁N₇O₇
global charge	-2
mol weight	471.43
InChIKey	VVIAGPKUTFNRDU-STQMWFEESA-L
InChI	InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/p-2/t12-,13-/m0/s1
SMILES	NC1=NC2=C(C(=O)N1)N(C=O)[C@@H](CNC1=CC=C(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])C=C1)CN2

MNX internals

InChI (mnx)	InChI=1/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
SMILES (mnx)	[CH:1]1=[CH:3][C:11]([NH:22][CH2:7][C@H:12]2[CH2:8][NH:23][C:16]3=[C:15]([C:18]([OH:32])=[N:26][C:20](=[NH:21])[NH:25]3)[N:27]2[CH:9]=[O:28])=[CH:4][CH:2]=[C:10]1[C:17]([NH:24][C@@H:13]([CH2:5][CH2:6][C:14](=[O:29])[OH:30])[C:19](=[O:33])[OH:34])=[O:31]

Parent-child relations graph

Occurences in reactions	#reac
in my sandbox	0
in MNXref (generic)	17
in models (compartimentalized)	13

Similar chemical compounds in external resources
Identifier	Description
CHEBI:57457 chebi:57457 VVIAGPKUTFNRDU-STQMWFEESA-L	(6S)-5-formyl-5,6,7,8-tetrahydrofolate (6S)-5-formyltetrahydrofolate(2-) 5-formyltetrahydrofolate dianion N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate
hmdb:HMDB0247218 VVIAGPKUTFNRDU-UHFFFAOYSA-N	(6R)-Folinic acid (6R,S)-5-Formyltetrahydrofolate 10-Formyl-7,8-dihydrofolate 10-Formyl-7,8-dihydrofolic acid 2-[(4-{[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid 2-[(4-{[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid 5 Formyltetrahydrofolate 5 Formyltetrahydropteroylglutamate 5-Formlyl-5,6,7,8-tetrahydrofolate,calcium salt 5-Formyl-5,6,7,8-tetrahydrofolate 5-Formyl-5,6,7,8-tetrahydrofolic acid 5-Formyltetrahydrofolate 5-Formyltetrahydrofolic acid 5-Formyltetrahydropteroylglutamate 5-Formyltetrahydropteroylglutamic acid Acid, folinic Calcium folinate Calcium leucovorin Citrovorum factor Factor, citrovorum Folinate Folinate, calcium Folinic acid Folinic acid SF Folinic acid-SF L(-)-5-Formyl-5,6,7,8-tetrahydrofolate L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid L-Leucovorin L-N-[P-[[(2-amino-5-Formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid Leucal Leucovorin Leucovorin, (D)-isomer Leucovorin, (DL)-isomer Leucovorin, (R)-isomer Leucovorin, calcium Leucovorin, calcium (1:1) salt Leucovorin, calcium (1:1) salt, (DL)-isomer Leucovorin, calcium (1:1) salt, pentahydrate Leucovorin, monosodium salt Leukovorin Leukovorum Levoleucovorin Monosodium salt leucovorin N(5)-Formyltetrahydrofolate N5-Formyl-5,6,7,8-tetrahydrofolate N5-Formyl-5,6,7,8-tetrahydrofolic acid N5-Formyltetrahydrofolate N5-Formyltetrahydrofolic acid Rescuvolin Welcovorin Wellcovorin
metacyc.compound:5-FORMYL-THF metacycM:5-FORMYL-THF VVIAGPKUTFNRDU-STQMWFEESA-L	(6S)-5-formyl-tetrahydrofolate mono-L-glutamate (6S)-leucovorin 5-CHO-THF monoglutamate 5-formyl-H4F monoglutamate 5-formyl-THF monoglutamate N5-formyl-H4F monoglutamate N5-formyl-H4PteGlu1 N5-formyl-THF monoglutamate citrovorum factor folinate folinic acid monoglutamate formyl-H4F monoglutamate n5-formyl-thf monoglutamate n5-formyltetrahydrofolate monoglutamate
CHEBI:63606 chebi:63606 VVIAGPKUTFNRDU-STQMWFEESA-N	(6S)-5-formyltetrahydrofolic acid (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid (6S)-Folinic acid (6S)-Leucovorin (S)-Leucovorin Citrovorum factor L-Folinic acid Levofolene Levofolinic acid N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid levoleucovorin
bigg.metabolite:5fothf biggM:5fothf VVIAGPKUTFNRDU-STQMWFEESA-L	5 Formyltetrahydrofolate
bigg.metabolite:5fthf biggM:5fthf VVIAGPKUTFNRDU-UHFFFAOYSA-L	5-Formyltetrahydrofolate
seed.compound:cpd02197 seedM:cpd02197 VVIAGPKUTFNRDU-STQMWFEESA-L	5-Formyltetrahydrofolate (6S)-5-formyl-tetrahydrofolate mono-L-glutamate (6S)-leucovorin 5-CHO-THF 5-CHO-THF monoglutamate 5-formyl-H4F 5-formyl-H4F monoglutamate 5-formyl-THF 5-formyl-THF leucovorin 5-formyl-THF monoglutamate 5-formyl-tetrahydrofolate 5fthf Folinic acid L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid Leucovorin N5-formyl-H4F N5-formyl-H4F monoglutamate N5-formyl-H4PteGlu1 N5-formyl-THF N5-formyl-THF monoglutamate citrovorum factor folinate folinic acid folinic acid monoglutamate formyl-H4F formyl-H4F monoglutamate n5-formyl-thf n5-formyl-thf monoglutamate n5-formyltetrahydrofolate n5-formyltetrahydrofolate monoglutamate
sabiork.compound:6654 sabiorkM:6654 VVIAGPKUTFNRDU-ABLWVSNPSA-N	5-Formyltetrahydrofolate Folinic acid L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid N5-Formyl-H4PteGlu1
hmdb:HMDB0304213 VVIAGPKUTFNRDU-UHFFFAOYSA-L	5-formyl-tetrahydrofolate 2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioate 2-[(4-{[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioate 4-Carboxy-4-[(4-{[(5-formyl-2-imino-4-oxido-1,2,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]butanoic acid 5-Formyl-tetrahydrofolic acid
CHEBI:65340 chebi:65340 VVIAGPKUTFNRDU-ABLWVSNPSA-L	5-formyltetrahydrofolate(2-) (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate
vmhM:5fthf vmhmetabolite:5fthf VVIAGPKUTFNRDU-STQMWFEESA-L	5-formyltetrahydrofolate(2-) (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
CHEBI:15640 chebi:15640 VVIAGPKUTFNRDU-ABLWVSNPSA-N	5-formyltetrahydrofolic acid (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate 10-Formyl-7,8-dihydrofolic acid 5-Formyl-5,6,7,8-tetrahydrofolic acid 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid 5-Formyltetrahydrofolate Acide folinique Folinic acid L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid Leucovorin Leucovorinum N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid N5-Formyl-5,6,7,8-tetrahydrofolic acid N5-Formyltetrahydrofolic acid folinate
kegg.drug:D07986 keggD:D07986 VVIAGPKUTFNRDU-UHFFFAOYSA-N	Folinic acid (BAN) Leucovorin Rescuvolin (TN)
hmdb:HMDB0001562 VVIAGPKUTFNRDU-STQMWFEESA-N	Folinic acid (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid (6S)-5-Formyl-5,6,7,8-tetrahydrofolate (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid (6S)-5-Formyltetrahydrofolate (6S)-5-Formyltetrahydrofolic acid (6S)-Folinate (6S)-Folinic acid (6S)-Leucovorin (S)-Leucovorin 5 Formyltetrahydrofolate 5 Formyltetrahydropteroylglutamate 5-Formyl-(6S)-tetrahydrofolic acid 5-Formyl-5,6,7,8-tetrahydrofolic acid 5-Formyltetrahydrofolate 5-Formyltetrahydrofolic acid 5-Formyltetrahydropteroylglutamate 5-Formyltetrahydropteroylglutamic acid 6 S Leucovorin 6-S-Leucovorin 6S Leucovorin 6S-Leucovorin Acid, folinic CF Calcium folinate Calcium leucovorin Citrovorum factor Factor, citrovorum Folinate Folinate, calcium Folinic acid SF Folinic acid-SF Fusilev Kunyrin L-Folinate L-Folinic acid Leucoverin Leucovorin Leucovorin, (D)-isomer Leucovorin, (DL)-isomer Leucovorin, (R)-isomer Leucovorin, (S)-isomer Leucovorin, calcium Leucovorin, calcium (1:1) salt Leucovorin, calcium (1:1) salt, (DL)-isomer Leucovorin, calcium (1:1) salt, (S)-isomer Leucovorin, calcium (1:1) salt, pentahydrate Leucovorin, monopotassium salt, (S)-isomer Leucovorin, monosodium salt Leucovorin, monosodium salt, (S)-isomer Leukovorin Leukovorum Levo leucovorin Levo-leucovorin Levofolene Levofolinate Levofolinic acid Levoleucovorin Monosodium salt leucovorin N(5)-Formyltetrahydrofolate N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid N5-Formyl-5,6,7,8-tetrahydrofolic acid N5-Formyl-THF N5-Formyltetrahydrofolic acid Pteroyl-D-glutamate S Leucovorin S-Leucovorin Welcovorin Wellcovorin
kegg.compound:C03479 keggC:C03479 VVIAGPKUTFNRDU-STQMWFEESA-N	Folinic acid 5-Formyltetrahydrofolate L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid Leucovorin
hmdb:HMDB0006206 hmdb:HMDB0062757 hmdb:HMDB01562 hmdb:HMDB06206 hmdb:HMDB62757 chebi:12127 chebi:18607 chebi:2057 biggM:M_5fothf biggM:M_5fthf keggC:M_C03479 keggD:M_D07986 seedM:M_cpd02197 vmhM:M_5fthf	secondary/obsolete/fantasy identifier